Cirrhosis is a complication of liver disease which involves loss of liver cells and irreversible scarring of the liver. Alcohol and viral hepatitis B and C are common causes of cirrhosis, although there are many other causes. Cirrhosis can cause weakness, loss of appetite, easy bruising, yellowing of the skin (jaundice), itching, and fatigue. Diagnosis of cirrhosis can be suggested by history, physical examination and blood tests, and can be confirmed by liver biopsy. Complications of cirrhosis include edema and ascites, spontaneous bacterial peritonitis, bleeding from varices, hepatic encephalopathy, hepatorenal syndrome, hepatopulmonary syndrome, hypersplenism, and liver cancer.
Stem cell treatment should be considered in patients with cirrosis. Therapy Consists in administration of autologous mesenchymal stem cells (MSC) isolated from patient’s adipose tissue or bone marrow.
The MSC are mixed with progenitor hepatocytes: anti-fibrosis growth factors; platelet rich plasma PRN and given intravenously.
The procedure is safe, painless and non-surgical. Liver function tests are done in 30 to 90 days post treatment. Many patients regain their liver functions soon after treatment.